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Nuvation Bio(NYSE) NUVB

Market Cap$2.13BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2020)-37%
5 Year-28%
1 Year+160%
1 Month+8%
$6.10
-4.32%
-0.27Today
After hours$6.12+$0.02 (+0.33%)
Nuvation Bio last closing stock price
MetricPriceDate
Last closeUSD 6.112026-08-06
Nuvation Bio stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week-8.81%USD 6.702026-07-30
1 month+7.76%USD 5.672026-07-07
3 month+27.56%USD 4.792026-05-08
Year to date-31.81%USD 8.962025-12-31
1 year+160%USD 2.352025-08-06
3 year+213.33%USD 1.952023-08-07
5 year-27.61%USD 8.442021-08-06
Since inception-37.01%USD 9.702020-08-26

Nuvation Bio Financials at a Glance

Market Cap

$2.13BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$169.90M

Net Income (TTM)

-$149.83M

EPS (TTM)

-$0.43

P/E Ratio

-14.27

Dividend

$0.00

Beta (Volatility)

1.38 (Average)

Price

$6.10

Volume

8,394,940

Open

$6.06

Previous Close

$6.11

Daily Range

$6.01 - $6.63

52-Week Range

$2.18 - $9.75

Estimated Earnings Date

Nov 2, 2026

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About Nuvation Bio

Nuvation Bio makes medicines for people fighting difficult types of cancer. Its treatments target specific proteins that cause tumors to grow and spread. The company helps patients find new options when standard therapies fail.

Fighting Cancer With Chemistry

  • IBTROZI: Oral drug for adults with a specific lung cancer called ROS1-positive non-small cell lung cancer.
  • Safusidenib: Targeted brain tumor treatment designed to pass through the blood-brain barrier to reach cancer cells.
  • Drug-Drug Conjugates: Technology platform that fuses two cancer-fighting molecules together to target tumors more precisely.
  • NUV-868: Small molecule that regulates proteins controlling tumor growth and differentiation.

How the Pipeline Is Growing

  • Acquired AnHeart Therapeutics Ltd. in April 2024 to add new clinical-stage programs to its pipeline.
  • Partnered with Eisai in January 2026 to develop and sell its lead drug in Europe and other territories.
  • Collaborated with Innovent to manage the development and commercial use of taletrectinib in China.
  • Signed an agreement with Nippon Kayaku to commercialize its lead product candidate in Japan.

What Makes the Science Different?

The Drug-Drug Conjugate platform creates treatments that are highly cell permeable and simpler to manufacture than traditional antibody-based drugs. The team uses deep medicinal chemistry experience to improve the safety and activity of oncology targets.

Recent Financial Performance

  • Revenue hit $41.9 million in Q4 2025, up 633.1% from Q4 2024.
  • Gross profit reached $41.4 million in Q4 2025, up 2,672% year over year.
  • Net losses narrowed to $36.6 million in Q4 2025, an improvement of 26% from Q4 2024.
  • Operating cash flow improved to a $29.7 million deficit in Q4 2025, up 35.8% from the prior year.

The Evolution of Nuvation

Nuvation Bio has evolved from a start-up into a global oncology company with its first approved drug. Its combination of internal research and strategic acquisitions supports its goal of solving tough challenges in cancer treatment.

AI Generated • May 4, 2026

Industry

Pharmaceuticals

Employees

298

CEO

David T. Hung, MD

Headquarters

New York City, NY 10036, US

NUVB Financials

Key Financial Metrics (TTM)

Gross Margin

88.90%

Operating Margin

-81.00%

Net Income Margin

-88.19%

Return on Equity

-49.73%

Return on Capital

-67.45%

Return on Assets

-20.12%

Earnings Yield

-7.01%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$2.13BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

349.20M

Volume

8.39M

Avg. Volume

6.40M

Financials (TTM)

Gross Profit

$159.60M

Operating Income

-$137.63M

EBITDA

-$127.04M

Operating Cash Flow

-$82.62M

Capital Expenditure

-$101.00K

Free Cash Flow

-$82.72M

Cash & ST Invst.

$660.96M

Total Debt

$252.14M

Nuvation Bio Performance Analysis

Nuvation Bio annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-12-31USD 0N/A
20232023-12-31USD 0N/A
20242024-12-31USD 7,873,000N/A
20252025-12-31USD 62,902,000699.0%
Nuvation Bio sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-30171.5%
Q42025-12-31219.1%
Q12026-03-3198.8%
Q22026-06-30-61.9%
Nuvation Bio annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-12-31USD -0.489.5%
20232023-12-31USD -0.35-28.0%
20242024-12-31USD -2.11510.2%
20252025-12-31USD -0.60-71.6%
Nuvation Bio sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q32025-09-305.9%
Q42025-12-3131.3%
Q12026-03-31113.0%
Q22026-06-30-1358.7%

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q2 2026YOY CHG

Revenue

$31.69M

+555.6%

Gross Profit

$30.78M

+1263.6%

Gross Margin

0.00%

N/A

Market Cap

$2.13BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$7.16M

N/A

Employees

298

N/A

Net Income

-$62.84M

-6.5%

EBITDA

-$55.55M

+4.6%

Quarterly Fundamentals

Name
Q2 2026YOY CHG

Total Cash

$660.96M

+8.8%

Total Debt

$252.14M

+336.5%

Accounts Receivable

$31.71M

+375.0%

Inventory

$19.90M

+3505.3%

Long Term Debt

$244.53M

+385.4%

Short Term Debt

$7.61M

+2.9%

Return on Assets

-20.12%

N/A

Return on Invested Capital

-20.92%

N/A

Free Cash Flow

-$5.02M

+89.6%

Operating Cash Flow

-$5.07M

+89.5%

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Questions About NUVB

What is the current price of Nuvation Bio?

Nuvation Bio is trading at $6.11 per share.

What is the 52-week range for Nuvation Bio?

Over the past 52 weeks, Nuvation Bio has traded between $2.18 and $9.75.

How much debt does Nuvation Bio have?

As of the most recent reporting period, Nuvation Bio reported total debt of $216.98M.

How much cash does Nuvation Bio have on hand?

Nuvation Bio reported $125.39M in cash and cash equivalents in its most recent financial results.

What is Nuvation Bio’s dividend yield?

Nuvation Bio does not currently have a dividend yield.

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