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Are Large-Cap or Small-Cap ETFs the Better Buy? Here's How SPY and IWO Stack Up on Risk and Returns

Explore how sector focus and risk profiles set these two popular ETFs apart for investors weighing growth potential against stability.

By Katie Brockman Mar 2, 2026 at 7:08PM EST

Key Points

  • IWO has delivered a higher one-year return but experienced a much steeper five-year drawdown than SPY.
  • SPY is more cost-effective and offers a higher dividend yield, while IWO charges higher fees for its small-cap growth focus.
  • IWO’s portfolio tilts heavily toward healthcare and industrials, contrasting with SPY’s large-cap tech dominance.

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