Logo of jester cap with thought bubble.

Image source: The Motley Fool.

Cryoport (NASDAQ:CYRX)
Q1 2019 Earnings Call
May. 02, 2019, 5:00 p.m. ET

Contents:

  • Prepared Remarks
  • Questions and Answers
  • Call Participants

Prepared Remarks:


Operator

Thank you for standing by. Welcome to the Cryoport first-quarter 2019 earnings call. [Operator instructions] And the conference is being recorded. [Operator instructions] I would now like to hand the conference over to Mr.

Todd Fromer. Please go ahead.

Todd Fromer -- Investor Relations

Thank you, operator. Good evening, everyone, and good afternoon to everyone on the West Coast. Before we begin today, I would like to remind everyone that this conference call contains certain forward-looking statements. All statements that address our operating performance, events or developments that we expect or anticipate occurring in the future are forward-looking statements.

These forward-looking statements are based on management's beliefs and assumptions and not on information currently available to our management team. Our management team believes these forward-looking statements are reasonable as and when made. However, you should not place undue reliance on any such forward-looking statements because such statements speak only as of the date when made. We do not undertake any obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

In addition, forward-looking statements are subject to certain risks and uncertainties that could cause actual results, events and developments to differ materially from our historical experiences and our present expectations or projections. These risks and uncertainties include, but are not limited to those described in item 1A, risk factors and elsewhere in our annual report on Form 10-K filed with the Securities and Exchange Commission and those described from time to time in other reports, which we filed with the Securities and Exchange Commission. With nothing further, I would now like to turn the call over to Mr. Jerry Shelton, chief executive officer of Cryoport.

Jerry, the floor is yours.

Jerry Shelton -- Chief Executive Officer

Thank you, Todd. And thank you, ladies and gentlemen, for joining us this afternoon. With me this afternoon is our chief financial officer, Mr. Robert Stefanovich; and our chief commercial officer, Dr.

Mark Sawicki. As a reminder, as of last quarter, we changed the format of these earnings calls. Instead of delivering prepared remarks, we have uploaded our first-quarter 2019 end review document to the Events and Presentation page of our Investor Relations website. This document provides a review of our recent financial and operational performance and a general business outlook.

So if you have not had a chance to read it, I would encourage you to go to our website and download it. On this conference call, I will provide a brief general update, and then, we will move into questions and answers, where we will address queries from our shareholders and analysts regarding our company's results. For an overview of our first-quarter 2019, revenue increased 65% to $6.7 million as compared to the same period in 2018. This growth was primarily driven by another strong quarter in the biopharma market where we reported $5.6 million in revenue, a 72% increase over the same period in the prior year.

Notably, $1.4 million of the quarter revenue was derived from commercial agreements with Novartis and Gilead, representing a 374% increase in commercial revenue compared with the same quarter in the prior year. Revenue from our commercial agreements is now 25% of total biopharma revenue. During the quarter, we continued to add the number of clinical stage therapies we support. And that addition of 26 new clinical trials were added in the first quarter, bringing the total number of trials, we now support to 383, which includes 45 in the EMEA region, 49 of these trials are in Phase 3 in total.

Our progress is reflected -- I'm sorry, our progress is reflective of the broader growth in the global regenerative medicine market as it continues its climb. We're pleased to report that the openings of our two new logistics centers located in Amsterdam, the Netherlands, and Livingston, New Jersey have been successful. As we scale the support of our existing -- with our existing clients, both these in clinical and commercial stages and onboard new clients, the short-term gross margin impact of these two new operations will decrease. Our gross margin target remains at 60%.

Today, Gilead, just after the market closed, reported that Yescarta generated $96 million in revenue during the first quarter of 2019, compared to $40 million for the same period in 2018. Our balance sheet is strong with $47 million in cash and cash equivalents reported at the end of the first quarter. As I have mentioned on the previous calls, a strong cash position is important to us for several reasons. First, it provides our clients with confidence and our stability in future.

And secondly, it provides us with financial flexibility to meet the increasingly complex and diverse requirements of the regenerative medicine market, including potential acquisition activity that has the ability to expand our range of solutions in a meaningful way. We're pleased to turn in another strong quarter, and we look forward to continuing to build our company and further enhancing our incomparable supply chain services to the rapidly growing and evolving life-sciences industry. We look forward to answering your questions. So now, I'll return the call to the operator to open the floor for questions.

Operator?

Questions & Answers:


Operator

[Operator instructions] Your first question comes from Andrew D'Silva from B. Riley FBR.

Andrew D'Silva -- B. Riley FBR, Inc. -- Analyst

Just a couple of quick questions on my end. Very comprehensive report, thanks for putting that out so early in the day. You touched on M&A as being a potential way to fill in some voids. I was just curious if you could give us a little bit of detail of what you're missing or what you could be looking for as we kind of think about the broader landscape? And then, actually, before you do that, if somebody could also just, while he's answering that question, pull cash flow from operations items? Just stock-based comp was there, but I was missing capex and free cash flow information.

Jerry Shelton -- Chief Executive Officer

Those are good questions, Andy. Thank you very much. The M&A, we've addressed consistently each quarter, and I wouldn't say anything this quarter any differently than we've said. We are looking methodically and carefully at acquisition candidates and potential candidates and those candidates who would be to either deepen the -- our solutions or in adjacencies.

And the comment -- the natural adjacencies would be in things like storage and other forms of software. That's our M&A activity. We do have a pipeline, and we are vigorously looking into the market place. But as you know, there's got to be a seller, as well as a buyer.

So acquisitions generally are opportunistic, and we are pursuing that avenue. As far as the second question, in terms of cash flow and expenses, I'm going to turn that to Robert Stefanovich for your answer.

Robert Stefanovich -- Chief Financial Officer, Treasurer, and Corporate Secretary

Yes. Just a couple of data points, and also, we'll be filing our 10-Q next Wednesday on May 8 as well. We have our capex about $1.1 million of -- for the quarter, net cash used and operating activities about $200,000, total financing activities about $1.3 million, and that's really cash receipts from the exercise of once primarily and then if we look at overall net cash used in investing activities, about $4.6 million. That's really just us investing the cash that we have.

We have about $15 million in short-term investments as all cash balance of $47.3 million.

Andrew D'Silva -- B. Riley FBR, Inc. -- Analyst

Yes. And I was trying to translate some of that off the balance sheet tied into the P&L and everything, but it looks like your cash burn is actually better than we were expecting at this point. Are you guys -- where you would expect to be? Or are you missing some additional overhead cost that we should expect to layer in? Or just kind of the real rate we should anticipate?

Robert Stefanovich -- Chief Financial Officer, Treasurer, and Corporate Secretary

Now if you look at what we did over 2018, and we talked about that and building out the infrastructure, building out quality systems and also the cost related to setting up the new global logistics centers in Amsterdam and in New Jersey. So a lot of that has happened 2018. So you look at it going forward in 2019, I would expect to really see that more flatten out. Certainly, we'll make investments as we go, but I'd expect it to be somewhat flat.

Andrew D'Silva -- B. Riley FBR, Inc. -- Analyst

OK. OK. Good. And then on the commercial partner front, you have a little bit of color on there? Is there may be a benchmark or a way to help us think about how many commercial partners you would anticipate having by the end of this year? At least help us kind of setup baseline expectation for how to model going into 2020 and 2021?

Jerry Shelton -- Chief Executive Officer

I'm going to turn that to Mark Sawicki for your answer.

Mark Sawicki -- Chief Commercial Officer

Yes, just a clarity. You're referring to actual commercialize on market or filed?

Andrew D'Silva -- B. Riley FBR, Inc. -- Analyst

On market.

Mark Sawicki -- Chief Commercial Officer

On market. So I think, on market, you may have one, maybe. I mean it depends on timing. Filed is a couple more than that I would say.

Andrew D'Silva -- B. Riley FBR, Inc. -- Analyst

OK. OK. Good. And just last question on my end is just related to new partners.

Obviously, you brought on Amgen and cellularity and handful of others this quarter, is there additional -- what is your target right now? I mean, it seems like you have a pretty good footprint around all the major players. Is there much more work that needs to be done on that side? Or is it just really growing within the market or the partners you reestablished relationships with?

Mark Sawicki -- Chief Commercial Officer

To be frank, it's both. I mean we're always trying to capture as much share as we can in the marketplace. I mean we think that we're in a very good position from a clinical trial acquisition standpoint. But we're not going to rest on our loyals.

We're going to continue to try to drive that number up as quickly and as aggressively as we can. And concurrently, try to, obviously, deepen and broaden the relationships that we already have established to drive per account or per clinical basis revenue up.

Operator

Your next question comes from Paul Knight from Janney Montgomery.

Paul Knight -- Janney Montgomery -- Analyst

Jerry, can you talk about what is driving this commercial. I mean, we see the improved revenue from the sales of these therapeutic lines of course. Is it -- they are also accelerating their network. It's obviously exceeding the growth rate of the therapeutics.

What's happening in this commercialization channel that you're having to do for them?

Jerry Shelton -- Chief Executive Officer

I'll turn that to Mark to answer, Paul, because he's closer to that than I am.

Mark Sawicki -- Chief Commercial Officer

I think, some of this, if you're talking about the average multiple on a per patient basis, they're diversifying the clinical base -- or commercial base of these accounts with additional country launches, moving material longer distances and into additional countries is more complex and inherently, obviously the cost basis would be slightly different than doing it for domestic U.S. distribution. I think that's probably what you're referring to, but clarify with me if you -- if that's not the intent you had?

Paul Knight -- Janney Montgomery -- Analyst

Yes. Your growth certainly is even exceeding their revenue ramp, which does seem to be better though.

Mark Sawicki -- Chief Commercial Officer

Yes. No, I agree. I mean, as I had mentioned before, as these relationships mature, the complexity of the revenue that's generated goes far beyond just strictly per shipment transaction.

Paul Knight -- Janney Montgomery -- Analyst

And then regarding the clinical trial customer, the Phase 1, 2, 3, what are you doing to increase revenue per customer? Are you charging for consulting? What do you do to pick up preclinical for customer revenue? Or even better ask the question.

Mark Sawicki -- Chief Commercial Officer

So that's absolutely right. I mean, what we're trying to do is, we're trying to provide a broader base of support and so consulting activity is a very good example, program management activity. Other things along those lines in addition to, obviously, the transactional distribution elements of a clinical trial.

Operator

Your next question comes from Brandon Couillard from Jefferies.

Brandon Couillard -- Jefferies -- Analyst

Jerry, I'd like to start on the new logistics centers in Livingston and Amsterdam. Could you just sort of elaborate on the revenue pull-through you are seeing at those sites? And whether you're really starting to actually pick up incremental business from the key customers of those sites perhaps with Bristol out of New Jersey? And then looking ahead, what are kind of your plans and priorities as far as adding additional logistics sites globally over the next 12 months?

Jerry Shelton -- Chief Executive Officer

Well, broadly, we're in the position now to -- that we're actually creating a logistics network and that network effect is our way of derisking the process even further. And that's what we're all about. We're about derisking the process and providing certainty to our clients. So now, we have five logistics centers, and at some point in the future, we'll add -- we definitely will add to that.

They will be client-driven however, and we aren't building things prospectively. We're building them based on demand and based on visibility of our client demand. As far as the two new logistics centers, they are right on track. Our demand is growing and both of those centers are right on track in terms of the volume increases and the volume uptake.

And in fact, we're looking -- we may have to look at expanding our footprint in both those locations at some point in the not-too-distant future.

Mark Sawicki -- Chief Commercial Officer

Let me just add to that. The sites definitely are contributing to bringing business in -- directly in the drawer from a proximity basis as well.

Brandon Couillard -- Jefferies -- Analyst

OK. And then we'd like to touch on Amgen if we could just for a moment. You sort of speak to the type of ramp you would expect with that customer. How long it takes you to sort of get integrated into the trials? If you could speak to perhaps the number of trials, you think you might be involved in with Amgen specifically? And then it would be curious to know exactly what type of solution they were previously using before your agreement?

Jerry Shelton -- Chief Executive Officer

That's a good question. Mark will answer that question.

Mark Sawicki -- Chief Commercial Officer

Yes. So just a couple of high level. Obviously, we can't comment on clinical trial strategy for Amgen. You'll have to look at what Amgen's predicting from that perspective.

But what I can tell you is that, we're very confident in this becoming a significant relationship. And I would anticipate, within the next 12 months, it will probably be a top 10 account pretty quickly. We're actively supporting all of their cryogenic distribution throughout the entire network, and this is picking up site by site, program by program and it extends beyond just clinical trial support and also extends into their research networks and all of their infrastructure related to R&D that may not have anything to do with cell and gene therapy.

Brandon Couillard -- Jefferies -- Analyst

OK. Super. One more. I would like to touch on if you can, just share with us an update on the C3 chipper and the adoption levels you kind of seen so far.

Whether or not it's been a material contributor to revenues yet and perhaps the number of customers or trials that have adopted that solution so far?

Jerry Shelton -- Chief Executive Officer

Yes. So we're definitely seeing adoption. This is the challenge that any new product is it takes time to get it written into clinical trial protocols and initiated, but we are absolutely seeing it supporting and increasing number of trials, and we anticipate that to continue to accelerate significantly.

Operator

[Operator instructions] Your next question comes from Richard Baldry from Roth Capital.

Richard Baldry -- ROTH Capital Partners -- Analayst

One of the bigger investment areas in the quarter look like sales and marketing, which is up about 20% sequentially. Now you've got pretty deep reach into the clinical trial area. So could you maybe talk to us about where those additional resources are targeting? Sort of what you feel -- we should expect for how fast those new marketing areas can be productive or generate incremental growth over the existing group you've got? Appreciate that.

Jerry Shelton -- Chief Executive Officer

Rich, thank you. That's a good question and Robert has an answer for you.

Robert Stefanovich -- Chief Financial Officer, Treasurer, and Corporate Secretary

Yes. So in general, you also know, we have direct sales force here in the U.S. We all start ramping up the sales force in Europe. We've expanded marketing activities.

And as part of the sales marketing, we have also parts of our logistics that are underlying and supporting the efforts, and then so we ramp-up the logistics support within that organization as well.

Operator

This concludes the question-and-answer session. I would like to hand the call back for closing remarks.

Jerry Shelton -- Chief Executive Officer

Thank you, operator, and thank you for your questions. And thank you for joining us today. We appreciate the opportunity to report to you and to have a dialogue. In closing, I would like to say, we're pleased with the quarter and the position that we occupy today.

We're building a strong global logistics network and are uniquely positioned to meet the global demands of our biopharma clients, both in clinical and commercial settings. It's also important to note that industry commercializations are just beginning, and revenue from our commercial agreements is rapidly ramping, and it is just the beginning. Our pledge to our long-term shareholders is that we will continue to work diligently to grow our client base across all of our markets and further build our value to the life sciences industry in a lasting and meaningful way. So until our next call, I bid you good evening.

Duration: 22 minutes

Call participants:

Todd Fromer -- Investor Relations

Jerry Shelton -- Chief Executive Officer

Andrew D'Silva -- B. Riley FBR, Inc. -- Analyst

Robert Stefanovich -- Chief Financial Officer, Treasurer, and Corporate Secretary

Mark Sawicki -- Chief Commercial Officer

Paul Knight -- Janney Montgomery -- Analyst

Brandon Couillard -- Jefferies -- Analyst

Richard Baldry -- ROTH Capital Partners -- Analayst

More CYRX analysis

All earnings call transcripts