Early-stage biotech companies commonly sell more shares in order to raise capital. After all, when you're pouring money into research and development but don't yet have a product approved to generate revenue, your hands are often tied. While investors don't like to see their slice of the profit pie shrink, secondary offerings are a necessary evil in the biotech world.

Learn more through the example of Puma Biotechnology (NASDAQ:PBYI) in this clip from Industry Focus: Healthcare.

A full transcript follows the video.

This podcast was recorded on Nov. 16, 2016.

Kristine Harjes: One recent secondary offering that was announced in the healthcare world was that of Puma Biotechnology. On Oct. 18, after the closing bell, they announced that they wanted to raise $150 million, and potentially another $22.5 million on top of that because of some technicalities with the people who underwrote the shares. They could technically have the option to buy them within 30 days, if they want. So, this was an interesting situation because Puma, right now, has this one drug called Neratinib. It's a breast cancer drug. If you were listening to this show yesterday, by the way, it's an HER2-positive breast cancer drug, which is a target that I was just talking about with Vince on the Consumer Goods show yesterday. Anyway, you have this drug, and it's under FDA review right now; the decision should come out in about mid-2017.

Gaby Lapera: That means they're still testing the drug?

Harjes: That means the trials have either largely wrapped up, or that they have enough that they could submit it to the FDA with what they have right now. The FDA is sitting on the information, they have the application, and they have a certain amount of time to actually accept or deny the drug the right to be marketed.

So, an approval, as you likely know, would send shares of this company higher. If you think about how the mechanics of shareholder dilution and secondary offerings work, you want to wait until you have that higher share price before you go out and sell more shares, because you make more money. But they don't really have enough time left, with the cash that they have, to wait for an actual approval. So, they had to do this now. And I think it's probably a smart move. They can hit the ground running; they can get ready for the launch. But shares did sink 18%, even before the price of this new, secondary offering was announced.

Since this announcement came out, shares have been slipping and slipping even more. Ultimately, shareholders were diluted about 15%, and the company got the money that they need. So, I think that's a fairly typical way you'll see secondary offerings and shareholder dilution in the biotech world. You have these companies that aren't making with the money with the drugs yet, because they're not approved yet, so they need to make money somehow.

This article represents the opinion of the writer, who may disagree with the “official” recommendation position of a Motley Fool premium advisory service. We’re motley! Questioning an investing thesis -- even one of our own -- helps us all think critically about investing and make decisions that help us become smarter, happier, and richer.