Please ensure Javascript is enabled for purposes of website accessibility

Gilead Sciences Says Remdesivir Hit the Mark in COVID-19 Trial

By Cory Renauer – Apr 29, 2020 at 11:14AM

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More

A phase 3 with the still-experimental antiviral treatment has met its primary endpoint.

Following some discouraging stories regarding remdesivir in recent days, Gilead Sciences (GILD 1.34%) on Tuesday shared two separate pieces of good news regarding its experimental antiviral drug. According to the company, a clinical trial of remdesivir in COVID-19 patients run by the National Institutes of Allergy and Infectious Diseases (NIAID) met its primary endpoint. Separately, the company shared positive results from one of its own remdesivir trials.

Primary endpoint met

It seems like a lifetime ago, but it was only February when the NIAID began its clinical trial with remdesivir, starting with a patient who had been quarantined aboard the Diamond Princess cruise ship. The multicenter study was expected to enroll around 800 patients hospitalized with COVID-19 symptoms and randomly place them into groups either receiving remdesivir or a placebo. 

Physician in an intensive care unit taking notes.

Image source: Getty Images.

The NIAID appointed data monitors to make interim assessments without unblinding providers and patients to which treatment group they were placed in. The NIAID has informed Gilead Sciences that the study met its primary endpoint -- time to recovery by day 29 following treatment -- but the government agency hasn't published results from the study or made an official announcement.

Consolation data

While it sounds like patients treated with remdesivir were quicker to recover, Gilead didn't share details, nor did it say whether NIAID provided any. The company did share details from the Simple-1 trial, which wasn't blinded and didn't employ a placebo group. Instead, the study simply compared recovery times from patients treated with a five-day regimen to recovery times for patients treated with a 10-day regimen.  

Results from the Simple-1 study suggest a longer course of treatment doesn't improve time to recovery. A majority of patients treated with a 5-day remdesivir regimen recovered within 10 days, while most patients treated with a 10-day regimen needed 11 days to recover.

Cory Renauer owns shares of Gilead Sciences. The Motley Fool owns shares of and recommends Gilead Sciences. The Motley Fool has a disclosure policy.

Invest Smarter with The Motley Fool

Join Over 1 Million Premium Members Receiving…

  • New Stock Picks Each Month
  • Detailed Analysis of Companies
  • Model Portfolios
  • Live Streaming During Market Hours
  • And Much More
Get Started Now

Stocks Mentioned

Gilead Sciences, Inc. Stock Quote
Gilead Sciences, Inc.
$63.17 (1.34%) $0.83

*Average returns of all recommendations since inception. Cost basis and return based on previous market day close.

Related Articles

Motley Fool Returns

Motley Fool Stock Advisor

Market-beating stocks from our award-winning analyst team.

Stock Advisor Returns
S&P 500 Returns

Calculated by average return of all stock recommendations since inception of the Stock Advisor service in February of 2002. Returns as of 09/27/2022.

Discounted offers are only available to new members. Stock Advisor list price is $199 per year.

Premium Investing Services

Invest better with The Motley Fool. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services.