Please ensure Javascript is enabled for purposes of website accessibility

Novavax Reports Positive Data From Animal Trial of Its COVID-19/Flu Combo Shot

By Taylor Carmichael - May 12, 2021 at 2:14PM

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More

Human trials of the combination vaccine are expected to start later this year.

Vaccine specialist Novavax (NVAX -0.78%) plans to file for an emergency use authorization with the Food and Drug Administration for its COVID-19 vaccine candidate in July. In addition, the biotech's vaccine candidate for influenza, NanoFlu, is waiting for a green light from the regulator. Last year, a phase 3 study of NanoFlu showed it to be superior to the market-leading flu vaccine from Sanofi (SNY 0.39%) in a head-to-head match-up.

This week, Novavax reported strong data from an animal study of a new inoculation that combines both of those promising vaccines.

The combo vaccine candidate was tested in hamsters and ferrets. Administered in a two-shot regimen, it produced a high level of antibodies against both flu and COVID-19 in the animals, comparable to the levels that were seen when either vaccine was tested alone. Significantly, hamsters who were immunized with the combo shot were challenged with SARS-CoV-2, and had no replicating coronavirus in their upper or lower respiratory tracts, nor did they have any signs of viral pneumonia. 

Masked doctor holds up vial of COVID-19 vaccine

image source: Getty Images

"This study's results build on our success to-date with NVX-CoV2373, and with NanoFlu, which successfully achieved all of its objectives in a pivotal Phase 3 trial announced last year," Dr. Gregory M. Glenn, Novavax's president of research and development, said in a press release. "We believe that this novel combination vaccine candidate, which leverages Novavax' technology platform and Matrix-M adjuvant, could be an important future tool in the long-term fight against both of these harmful respiratory viruses."

Moderna (MRNA -0.93%) also plans to produce a combination vaccine, but so far is trailing Novavax in that effort. Novavax stock was down by 6.6% as of 2 p.m. EDT on Wednesday, while the S&P 500 was off by 1.7%.

Taylor Carmichael owns shares of Novavax. The Motley Fool recommends Moderna Inc. The Motley Fool has a disclosure policy.

Invest Smarter with The Motley Fool

Join Over 1 Million Premium Members Receiving…

  • New Stock Picks Each Month
  • Detailed Analysis of Companies
  • Model Portfolios
  • Live Streaming During Market Hours
  • And Much More
Get Started Now

Stocks Mentioned

Novavax, Inc. Stock Quote
Novavax, Inc.
$36.89 (-0.78%) $0.29
Sanofi Stock Quote
$41.35 (0.39%) $0.16
Moderna, Inc. Stock Quote
Moderna, Inc.
$148.60 (-0.93%) $-1.40

*Average returns of all recommendations since inception. Cost basis and return based on previous market day close.

Related Articles

Motley Fool Returns

Motley Fool Stock Advisor

Market-beating stocks from our award-winning analyst team.

Stock Advisor Returns
S&P 500 Returns

Calculated by average return of all stock recommendations since inception of the Stock Advisor service in February of 2002. Returns as of 08/19/2022.

Discounted offers are only available to new members. Stock Advisor list price is $199 per year.

Premium Investing Services

Invest better with The Motley Fool. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services.