Express Scripts Holding (Nasdaq: ESRX) reported earnings on May 10. Here are the numbers you need to know.

The 10-second takeaway
For the quarter ended March 31 (Q1), Express Scripts Holding beat expectations on revenues and missed estimates on earnings per share.

Compared to the prior-year quarter, revenue increased and GAAP earnings per share dropped.

Gross margins grew, operating margins contracted, and net margins dropped.

Revenue details
Express Scripts Holding notched revenue of $12.13 billion. The 18 analysts polled by S&P Capital IQ foresaw net sales of $11.48 billion on the same basis. GAAP reported sales were 9.4% higher than the prior-year quarter's $11.09 billion.

Source: S&P Capital IQ. Quarterly periods. Dollar amounts in millions. Non-GAAP figures may vary to maintain comparability with estimates.

EPS details
EPS came in at $0.73. The 22 earnings estimates compiled by S&P Capital IQ forecast $0.77 per share. GAAP EPS of $0.55 for Q1 were 9.8% lower than the prior-year quarter's $0.61 per share.

Source: S&P Capital IQ. Quarterly periods. Non-GAAP figures may vary to maintain comparability with estimates.

Margin details
For the quarter, gross margin was 6.9%, 20 basis points better than the prior-year quarter. Operating margin was 4.7%, 30 basis points worse than the prior-year quarter. Net margin was 2.2%, 70 basis points worse than the prior-year quarter.

Looking ahead
Next quarter's average estimate for revenue is $25.99 billion. On the bottom line, the average EPS estimate is $0.87.

Next year's average estimate for revenue is $91.39 billion. The average EPS estimate is $3.64.

Investor sentiment
The stock has a four-star rating (out of five) at Motley Fool CAPS, with 698 members out of 741 rating the stock outperform, and 43 members rating it underperform. Among 186 CAPS All-Star picks (recommendations by the highest-ranked CAPS members), 178 give Express Scripts Holding a green thumbs-up, and eight give it a red thumbs-down.

Of Wall Street recommendations tracked by S&P Capital IQ, the average opinion on Express Scripts Holding is outperform, with an average price target of $61.75.

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Seth Jayson had no position in any company mentioned here at the time of publication. You can view his stock holdings here. He is co-advisor of Motley Fool Hidden Gems, which provides new small-cap ideas every month, backed by a real-money portfolio. Motley Fool newsletter services have recommended buying shares of Express Scripts Holding. Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.