Based on the aggregated intelligence of 180,000-plus investors participating in Motley Fool CAPS, the Fool's free investing community, stem-cell company Osiris Therapeutics (Nasdaq: OSIR) has received the dreaded one-star ranking.

With that in mind, let's take a closer look at Osiris and see what CAPS investors are saying about the stock right now.

Osiris facts

Headquarters (Founded) Columbia, Md. (1992)
Market Cap $363.2 million
Industry Biotechnology
Trailing-12-Month Revenue $27.9 million
Management CEO Dr. Charles Mills (since 2004)
CFO Philip Jacoby Jr. (since 2009)
Return on Equity (Average, Past 3 Years) 12%
Cash/Debt $38.8 million / $0
Competitors Abbott Labs
Biogen Idec
UCB S.A.

Sources: S&P Capital IQ and Motley Fool CAPS.

On CAPS, 51% of the 73 All-Star members who have rated Osiris believe the stock will underperform the S&P 500 going forward.

Earlier this week, one of those Fools, All-Star BlacknGold, tapped Osiris as a particularly speculative selection:

Hopefully this speculative pharma red-thumb doesn't hurt me like some others have these past few months. I tend to agree with those who are realistic about the company's recent nod on Prochymal and ask "Yeah, so what?" This is tough for me because I am an absolute believer in the gargantuan impact stem cells will one day have on society. However, there are still too many obstacles and questions that remained to be answered.

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