In the following video, Motley Fool Chief Investment Officer Andy Cross takes a question from a Fool reader, who asks, "The lifelong question. When to sell. I'm great at timing buying, but waffle about when to take profits or cut losses."

Try any of our Foolish newsletter services free for 30 days. We Fools may not all hold the same opinions, but we all believe that considering a diverse range of insights makes us better investors. The Motley Fool has a disclosure policy.