In the spirit of World Cup competition, we're holding our own tournament in search of the Better Stock Today. We're pitting 32 companies against each other and you, the reader, will determine the winner.

Today it's the round of 16, and Isis Pharmaceuticals (IONS 2.58%) takes on Energy Transfer Partners (ETP) in our search for the better stock.

David Williamson, Motley Fool health care analyst, thinks Isis should advance to the next round because of one big reason -- its amazing drug pipeline. Wall Street heralds it as the best in biotech and puts Isis in play as a takeover target. A virtual who's who of big pharma has struck partnership deals. Isis already has orphan drug Kynamro on the market, and has seen recent success from a mid-stage study for an anti-clotting drug. A recent sell-off has given investors a chance to get this deep pipeline at a discounted price.

Joel South, energy analyst at The Motley Fool, thinks Energy Transfer Partners is a great investment for dividend lovers. The Master Limited Partnership currently distributes a very respectable 6.6% yield, but with strong segment diversification, a proven track record of executing on project backlogs and a built out pipeline infrastructure ready to service U.S. LNG exports, distributable cash flows should continue to pick up for unitholders.

Vote here to determine the winner of this match and sound off in the comments. Check back to Fool.com to see who advances in the tournament.