Based on the aggregated intelligence of 180,000-plus investors participating in Motley Fool CAPS, the Fool's free investing community, biotechnology company Threshold Pharmaceuticals (Nasdaq: THLD) has received a distressing two-star ranking.

With that in mind, let's take a closer look at Threshold's business and see what CAPS investors are saying about the stock right now.

Threshold facts

Headquarters (founded) San Francisco, Calif. (2001)
Market Cap $430.5 million
Industry Biotechnology
Trailing-12-Month Revenue $314.0 thousand
Management Chairman/CEO Dr. Harold Selick (since 2002)
Principal Financial Officer Joel Fernandes (since 2007)
Return on Assets (average, past 3 years) (37.0%)
Cash/Debt $49.7 million / $0
Competitors Eli Lilly
Pfizer

Sources: S&P Capital IQ and Motley Fool CAPS.

On CAPS, 23% of the 101 members who have rated Threshold believe the stock will underperform the S&P 500 going forward.

Just yesterday, one of those bears, All-Star zzlangerhans, tapped the stock as a particularly risky proposition:

Rising summer tides have bought Threshold back close to recent highs seen shortly after the company partnered TH-302 with Merck KGaA and then reported significant [progression-free survival] improvement in [pancreatic cancer] in trial 404. Those tides have left the stock vulnerable to a sharp decline if the OS data from the same trial to be reported this half don't match lofty expectations.

If you want market-thumping returns, you need to put together the best portfolio you can. Owning exceptional stocks is a surefire way to secure your financial future. Threshold, with its two-star rating, may not fit the bill for your portfolio.

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Fool contributor Brian Pacampara owns no position in any of the companies mentioned. Motley Fool newsletter services have recommended buying shares of Pfizer. Try any of our Foolish newsletter services free for 30 days.

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