Emerging from the financial crisis, the government has implemented new regulations squarely aimed at the big banks like Bank of America (BAC -0.13%) and JPMorgan Chase (JPM 0.49%). The latest potential hit is a proposed tax on the largest financial institutions that breach a given asset threshold. After additional costs from regulations like the Volcker Rule and loss of revenue due to things like interchange reform, is it finally time to start worrying about banks' profitability?

In this segment of The Motley Fool's financials-focused show, Where the Money Is, banking analysts Matt Koppenheffer and David Hanson debate the impact of these regulations and how it influences how they view bank stock multiples.