Rumors have been swirling lately that Walgreen (WBA 0.61%) will attempt to move early on its option to purchase the remaining 55% of British retail pharmacy Alliance Boots (it already owns 45% of the company). While it doesn't look particularly likely that Walgreen will actually move early, the contract it has with Boots stipulates that Walgreen could go ahead with the massive transaction starting next February.

So, the #1 question investors should ask about this potential acquisition is obvious: Would the combination make sense? 

In the video below, from Market Checkup, the Motley Fool's health care-focused investing show, health care analysts Michael Douglass and David Williamson lay out the potential synergies between Walgreen and Alliance Boots and their take on the potential deal.