Please ensure Javascript is enabled for purposes of website accessibility

In Addition, Our Drug Actually Rocks

By Brian Orelli, PhD - Updated Apr 6, 2017 at 8:59PM

You’re reading a free article with opinions that may differ from The Motley Fool’s Premium Investing Services. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Learn More

Pfizer and Bristol get good data on Eliquis.

The press release touting Pfizer (NYSE: PFE) and Bristol-Myers Squibb's (NYSE: BMY) atrial fibrillation drug makes the whole thing sound like an afterthought: "In addition, Eliquis met the key secondary endpoints of superiority on efficacy and on ISTH (International Society on Thrombosis and Haemostasis) major bleeding compared to warfarin."

But those 26 words could be worth billions to Pfizer and Bristol-Myers Squibb. Yes, billions.

It's a three-horse race to replace warfarin: Eliquis, Boehringer Ingelheim's Pradaxa, and Xarelto from Bayer and Johnson & Johnson (NYSE: JNJ). There's data that shows Pradaxa is superior to warfarin, but it wasn't a blinded study -- patients knew which drug they were getting -- so it's not considered all that strong. Xarelto failed to beat warfarin in atrial fibrillation patients.

Pfizer and Bristol-Myers hedged their bets making non-inferiority to warfarin the primary endpoint with superiority as the secondary endpoint, which is the reason the duo didn't lead with the more important news. Proving that Eliquis is as good as warfarin -- and its nasty side effect of major bleeding -- would have been good enough to get Eliquis on the market. Topping warfarin on efficacy and safety should be enough to rocket past Pradaxa and Xarelto.

The companies plan on submitting marketing applications for Eliquis in the U.S. and Europe later this year, which would make it the third drug to make it to market. Being third to the party with ho-hum data would result in ho-hum sales for sure. With superior data -- assuming they live up to the hype of the press release -- Pfizer and Bristol-Myers can expect major sales from Eliquis.

Looking for more stock ideas? Here are five stocks that The Motley Fool owns and its analysts think you should, too.

Invest Smarter with The Motley Fool

Join Over 1 Million Premium Members Receiving…

  • New Stock Picks Each Month
  • Detailed Analysis of Companies
  • Model Portfolios
  • Live Streaming During Market Hours
  • And Much More
Get Started Now

Stocks Mentioned

Pfizer Inc. Stock Quote
Pfizer Inc.
$51.97 (0.74%) $0.38
Bristol Myers Squibb Company Stock Quote
Bristol Myers Squibb Company
$80.11 (1.46%) $1.16
Johnson & Johnson Stock Quote
Johnson & Johnson
$182.66 (0.20%) $0.36

*Average returns of all recommendations since inception. Cost basis and return based on previous market day close.

Related Articles

Motley Fool Returns

Motley Fool Stock Advisor

Market-beating stocks from our award-winning analyst team.

Stock Advisor Returns
S&P 500 Returns

Calculated by average return of all stock recommendations since inception of the Stock Advisor service in February of 2002. Returns as of 06/27/2022.

Discounted offers are only available to new members. Stock Advisor list price is $199 per year.

Premium Investing Services

Invest better with The Motley Fool. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services.