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Twist Bioscience(NASDAQ) TWST

Market Cap$9.37BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.
Since IPO (2018)+917%
5 Year+42%
1 Year+416%
1 Month+63%
$142.50
+0.08%
+0.11Today
Twist Bioscience last closing stock price
MetricPriceDate
Last closeUSD 142.392026-08-19
Twist Bioscience stock price return by period
PeriodPrice returnPrice at period startPeriod start date
1 week+13.72%USD 125.212026-08-12
1 month+62.82%USD 87.452026-07-20
3 month+142.02%USD 58.842026-05-21
Year to date+348.9%USD 31.722025-12-31
1 year+416.28%USD 27.582025-08-19
3 year+631.71%USD 19.462023-08-18
5 year+41.7%USD 100.492021-08-20
Since inception+917.07%USD 14.002018-10-31

Twist Bioscience Financials at a Glance

Market Cap

$9.37BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Revenue (TTM)

$431.80M

Net Income (TTM)

-$136.72M

EPS (TTM)

-$2.22

P/E Ratio

-64.03

Dividend

$0.00

Beta (Volatility)

2.37 (High)

Price

$142.50

Volume

1,148,740.634

Open

$136.84

Previous Close

$142.39

Daily Range

$136.37 - $145.51

52-Week Range

$23.30 - $145.51

Estimated Earnings Date

Nov 13, 2026

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About Twist Bioscience

Twist Bioscience makes custom DNA for scientists and drug companies. It uses silicon chips to write genetic code quickly and cheaply. These products help researchers find medicines and improve medical tests.

Building Blocks of Biology

  • NGS Applications: Tools for next-generation sequencing (NGS), which is the process of reading DNA to find genetic markers; represented 52% of revenue in the nine-month period ended June 30, 2026.
  • DNA Synthesis and Protein Solutions: Custom DNA fragments, genes, and proteins used for research and drug discovery; accounted for 48% of revenue in the nine-month period ended June 30, 2026.
  • Synthetic Genes: Individual sequences of genetic material manufactured for customers in agriculture, chemicals, and academic research.

Scaling the Platform

  • Acquired a 6.24% ownership stake in Invenra Inc. in February 2026 to access a proprietary platform for antibody discovery.
  • Established a $200 million equity program in June 2026 to allow for the potential sale of common stock.
  • Sold the DNA digital data storage business in fiscal year 2025 to focus on core synthesis and sequencing products.
  • Expanded the South San Francisco headquarters in November 2025 to consolidate multiple office locations.

What Makes Twist Different?

Twist utilizes a proprietary silicon-based platform to manufacture DNA with higher precision and lower costs than older chemical methods. The company serves over 3,800 customers annually through a direct sales team and an online store for ordering custom genetic materials.

Tracking the Numbers

  • Total revenues rose 20% to $332.8 million during the nine-month period ended June 30, 2026.
  • Gross margin reached 52.1% in the nine months ended June 30, 2026, up from 50.5% in the prior year period.
  • Net loss was $109.6 million for the nine-month period ended June 30, 2026.
  • Cash, cash equivalents, and short-term investments totaled $166.8 million as of June 30, 2026.
  • Accumulated deficit reached $1,429.2 million as of June 30, 2026.

Evolution of Synthetic DNA

Twist has transitioned from a DNA manufacturer into a provider of integrated biological tools for healthcare and industrial research. The company continues to prioritize revenue growth and manufacturing scale while managing significant historical losses.

AI Generated • Aug 4, 2026

Industry

Biotechnology

Employees

979

CEO

Emily Marine Leproust, PhD

Headquarters

South San Francisco, CA 94080, US

TWST Financials

Key Financial Metrics (TTM)

Gross Margin

51.97%

Operating Margin

-31.91%

Net Income Margin

-31.66%

Return on Equity

-29.89%

Return on Capital

-22.33%

Return on Assets

-20.33%

Earnings Yield

-1.56%

Dividend Yield

0.00%

Payout Ratio

0.00%

Stock Overview

Market Cap

$9.37BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

Shares Outstanding

65.83M

Volume

1.15M

Avg. Volume

1.80M

Financials (TTM)

Gross Profit

$224.39M

Operating Income

-$137.77M

EBITDA

-$107.79M

Operating Cash Flow

-$53.07M

Capital Expenditure

-$40.05M

Free Cash Flow

-$93.12M

Cash & ST Invst.

$166.84M

Total Debt

$93.59M

Twist Bioscience Performance Analysis

Twist Bioscience annual revenue and year-over-year revenue growth by fiscal year
Fiscal yearPeriod endRevenueYoY growth
20222022-09-30USD 203,565,00053.8%
20232023-09-30USD 245,109,00020.4%
20242024-09-30USD 312,974,00027.7%
20252025-09-30USD 376,572,00020.3%
Twist Bioscience sequential (quarter-over-quarter) revenue growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q42025-09-303.1%
Q12025-12-314.7%
Q22026-03-316.8%
Q32026-06-306.9%
Twist Bioscience annual diluted earnings per share and year-over-year EPS growth by fiscal year
Fiscal yearPeriod endDiluted EPSYoY growth
20222022-09-30USD -4.0428.3%
20232023-09-30USD -3.60-11.0%
20242024-09-30USD -3.600.0%
20252025-09-30USD -1.30-63.9%
Twist Bioscience sequential (quarter-over-quarter) diluted earnings per share growth by fiscal quarter
Fiscal quarterPeriod endQoQ growth
Q42025-09-30-236.4%
Q12025-12-31-11.1%
Q22026-03-31-42.0%
Q32026-06-3021.1%

Revenue Growth Rate

Annual and quarterly growth comparison

Earnings Per Share Growth Rate

Annual and quarterly EPS growth comparison

Quarterly Performance

Name
Q3 2026YOY CHG

Revenue

$118.38M

+23.2%

Gross Profit

$62.45M

+21.7%

Gross Margin

52.76%

N/A

Market Cap

$9.37BMarket cap calculated using publicly traded shares outstanding only. Does not include unlisted, private, or dual-class non-traded shares. Implied market cap may vary.

N/A

Market Cap/Employee

$9.57M

N/A

Employees

979

N/A

Net Income

-$35.05M

-271.9%

EBITDA

-$27.96M

-206.0%

Quarterly Fundamentals

Name
Q3 2026YOY CHG

Total Cash

$166.84M

-33.5%

Total Debt

$93.59M

+19.8%

Accounts Receivable

$65.76M

+31.9%

Inventory

$35.16M

+35.6%

Long Term Debt

$84.96M

+35.6%

Short Term Debt

$8.63M

-44.3%

Return on Assets

-20.33%

N/A

Return on Invested Capital

-24.95%

N/A

Free Cash Flow

-$8.55M

+19.1%

Operating Cash Flow

$1.12M

+179.6%

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Questions About TWST

What is the current price of Twist Bioscience?

Twist Bioscience is trading at $142.94 per share.

What is the 52-week range for Twist Bioscience?

Over the past 52 weeks, Twist Bioscience has traded between $23.30 and $145.51.

How much debt does Twist Bioscience have?

As of the most recent reporting period, Twist Bioscience reported total debt of $93.59M.

How much cash does Twist Bioscience have on hand?

Twist Bioscience reported $117.44M in cash and cash equivalents in its most recent financial results.

What is Twist Bioscience’s dividend yield?

Twist Bioscience does not currently have a dividend yield.

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