Best Vaccine Stocks | The Motley Fool

Learn about the companies that are manufacturing vaccines and what you should know before investing in vaccine stocks.

By Keith Speights – Updated Sep 1, 2025 at 2:44 PM | Fact-checked by Frank Bass

Key Points

COVID-19 vaccine sales are down, yet still bring substantial revenue to manufacturers.
Top vaccine companies like Pfizer not only market COVID-19 vaccines but also other immunizations and drugs.
Before investing, examine a vaccine stock's market presence, regulatory status, and product diversification.

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Doctor giving patient a vaccine shot. — Image source: Getty Images.

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Ticker Information Table
Name and ticker	Market cap	Dividend yield	Industry
Pfizer (NYSE:PFE)	$141.3 billion	6.88%	Pharmaceuticals
BioNTech Se (NASDAQ:BNTX)	$25.7 billion	0.00%	Biotechnology
Moderna (NASDAQ:MRNA)	$10.7 billion	0.00%	Biotechnology
GSK (NYSE:GSK)	$88.3 billion	3.75%	Pharmaceuticals
Bavarian Nordic A/s (OTC:BVNR.Y)	$2.9 billion	0.00%	Biotechnology
Emergent BioSolutions (NYSE:EBS)	$504.2 million	0.00%	Biotechnology

Data as of Oct 22, 2025.

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NYSE: PFE

Pfizer

Today's Change

(-0.52%) $-0.13

Current Price

$24.72

Key Data Points

Market Cap

$141B

Day's Range

$24.62 - $24.93

52wk Range

$20.91 - $29.17

Volume

49M

Avg Vol

49M

Gross Margin

67.34%

Dividend Yield

0.07%

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NASDAQ: BNTX

BioNTech Se

Today's Change

(-0.62%) $-0.66

Current Price

$106.23

Key Data Points

Market Cap

$26B

Day's Range

$105.00 - $107.05

52wk Range

$81.20 - $129.27

Volume

797K

Avg Vol

878K

Gross Margin

79.80%

Dividend Yield

N/A

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NASDAQ: MRNA

Moderna

Today's Change

(-2.33%) $-0.64

Current Price

$26.85

Key Data Points

Market Cap

$11B

Day's Range

$26.27 - $27.35

52wk Range

$23.15 - $57.69

Volume

7.9M

Avg Vol

10M

Gross Margin

45.74%

Dividend Yield

N/A

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4. GSK

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NYSE: GSK

GSK

Today's Change

(0.73%) $0.32

Current Price

$44.26

Key Data Points

Market Cap

$88B

Day's Range

$44.01 - $44.47

52wk Range

$31.71 - $45.59

Volume

Avg Vol

4.7M

Gross Margin

71.69%

Dividend Yield

0.04%

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Investing in the Best Healthcare Stocks

Healthcare is a universal need. Companies in this broad-based sector can produce healthy returns.

Biotech vs. Pharma: What's the Difference?

While there is a lot of overlap between biotech and pharma, there are some key differences.

Pharmaceutical tariffs: Which countries does the U.S. import the most from?

The United States has a $115.5 billion trade deficit in pharmaceutical products, read on for more drug manufacturing stats.

Investing in Biotech Stocks in 2025

These companies create drugs and treatments for some of the biggest medical problems of our time.

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OTC: BVNR.Y

Bavarian Nordic A/s

Today's Change

(0.04%) $0.01

Current Price

$12.46

Key Data Points

Market Cap

$3B

Day's Range

$12.46 - $12.47

52wk Range

$6.59 - $13.00

Volume

Avg Vol

7.5K

Gross Margin

53.19%

Dividend Yield

N/A

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Emergent Biosolutions (EBS -0.21%) is probably best known for its anthrax vaccines and Narcan nasal spray for the emergency treatment of opioid overdoses. However, the company also markets other products, including smallpox and mpox vaccine ACAM2000.

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NYSE: EBS

Emergent BioSolutions

Today's Change

(-0.21%) $-0.02

Current Price

$9.43

Key Data Points

Market Cap

$1B

Day's Range

$9.13 - $9.54

52wk Range

$4.02 - $12.73

Volume

616K

Avg Vol

1.1M

Gross Margin

46.25%

Dividend Yield

N/A

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About the Author

Keith Speights is a contributing Motley Fool healthcare analyst covering publicly traded companies across pharmaceuticals, biotechnology, medical devices, technology, and marijuana. Prior to The Motley Fool, Keith was CEO of Constant Care Technology, a healthcare technology company; vice president of American HealthTech, a healthcare software company; and a director of operations for Blue Cross Blue Shield of Mississippi, a health insurer. He holds a B.S. in Industrial Engineering from Mississippi State University.

TMFFishBiz

Keith Speights has positions in Pfizer. The Motley Fool has positions in and recommends Merck and Pfizer. The Motley Fool recommends BioNTech Se, Emergent BioSolutions, GSK, and Moderna. The Motley Fool has a disclosure policy.

Investing in Vaccine Stocks

Learn about the companies that are manufacturing vaccines and what you should know before investing in vaccine stocks.

Key Points

Key Data Points

Key Data Points

Key Data Points

4. GSK

Key Data Points

Investing in the Best Healthcare Stocks

Biotech vs. Pharma: What's the Difference?

Pharmaceutical tariffs: Which countries does the U.S. import the most from?

Investing in Biotech Stocks in 2025

Key Data Points

Key Data Points

About the Author

Premium Investing Services

Investing in the Best Healthcare Stocks

Biotech vs. Pharma: What's the Difference?

Pharmaceutical tariffs: Which countries does the U.S. import the most from?

Investing in Biotech Stocks in 2025

Key Data Points

Key Data Points

Key Data Points

Key Data Points

Key Data Points

What companies make COVID vaccines?

What is the future price of MRNA stock?

Who owns Pfizer?

What to know about investing in vaccine stocks

Top vaccine stocks

1. Pfizer

4. GSK

Other vaccine stocks to watch

FAQ

Related investing topics

Key Data Points

2. BioNTech

3. Moderna