It's the end of 2012, and that means it's time to take a look back at the year in retrospect. We'll be reading through the naughty and nice list (we've already checked it twice), counting down the 25 best-performing stocks and the 25 worst-performing stocks in the health care sector this year.

In this segment, Motley Fool health care analysts Brenton Flynn and Max Macaluso take a look at No. 25 on the naughty list, Trius Therapeutics, and why this company deserves coal in its stocking.