Technically, you should sell Keryx Biopharmaceuticals (Nasdaq: KERX) right now.

We examined the company using moving average convergence-divergence (MACD), which is one of the most popular and long-used technical analysis indicators. Technical analysis is the field of buying and selling stocks not based on the underlying merits of a company, but rather on the patterns and formulas around its price movements.

Signal line crossover is one of the more common ways to interpret MACD. It uses a series of moving averages (in this case, nine, 12, and 26 days) to look for bullish and bearish crossovers that indicate a stock has momentum in one direction or another. Below you can find a current chart of Keryx Biopharmaceuticals' MACD profile:

Confused? Well, that's preposterous! How could you ever be confused by something as simple as a moving average convergence-divergence chart! OK, we jest -- but in all seriousness, this is actually one of the simpler methods for technical analysis.

Still, if you'd strictly followed the rules, seeking out upward and downward momentum, you would have seen the stock move between buy and sell categories a fantastic 16 times in one year!

A better way to size up companies
Here at, we're more interested in other measures of company value. When we look at Keryx Biopharmaceuticals and its peers, here are the areas that interest us:


Keryx Biopharmaceuticals

Eli Lilly (NYSE: LLY)

Genzyme (Nasdaq: GENZ)

United Therapeutics (Nasdaq: UTHR)

Market Cap (millions)





Net Income (TTM, millions)





EBIT (TTM, millions)





Source: Capital IQ, a division of Standard and Poor's; TTM = trailing 12 months; EBIT = earnings before interest and taxes.

We prefer to look at the fundamental drivers of value. Investors should closely watch statistical fields like return on equity as well as qualitative values like competitive advantage and managerial effectiveness. These areas led investors like Warren Buffett and Seth Klarman to decades of outperformance. Buying and holding great companies is the best solution for individual investors to build lasting wealth and achieve their financial goals.

  • So when you look at Keryx Biopharmaceuticals, don't evaluate it for crossing a momentum line. Buy or sell it because Keryx has ambitious plans, with treatments for both cancer and kidney disease in development.
  • However, the company doesn't have any products on the market yet. It recently reported an expanded loss as it doubled research and development spending. The company is in late-stage trials for two major treatments: perifosine, a cancer treatment, and Zerenex, which treats high phosphate levels in patients with end-stage kidney disease.
  • With several phase 3 trials under way, there is likely to be some major spikes in either the positive or negative direction when the company announces clinical trial results, as well as when the Food and Drug Administration announces its decisions, if things get that far. Investors not comfortable with the high possibility of losses should stay clear of this stock.

Want to sell Keryx Biopharmaceuticals based on technical merits today? Technically, odds are that you should flip and buy Keryx Biopharmaceuticals sometime very soon. If that sounds like madness to you, well, we here at agree. In every market decline, technical analysis gets its share of proponents. The cries that "buy-and-hold is dead!" get louder, and individuals race toward schemes that promise greater wealth in a shorter amount of time.

I don't deny that technical analysis could make investors money. In any random short-term transaction, you're essentially playing a 50/50 game of chance. However, at the same time, most technical analysis schemes are a relatively simple science, eliminating the vast complexities of evaluating true company value. However attractive, this theory is ultimately the wrong path for individual investors. Technical analysis relies on long-held beliefs about exploiting momentum and consistent patterns throughout the market.

However, with as much as 75% of market trading now done by Ph.D.-level programmers at massive high-frequency funds, even if opportunities existed, what chance would an individual have to sniff these deals out? With so much volume now driven by these funds, how can you be certain the same rules of patterns still even exist?

I could also point to Massey University's study across 49 countries, which showed that more than 5,000 trading rules add no value. However, the real reason to forget about technical investing is what we mentioned earlier: Keryx Biopharmaceuticals crossed the crossover 16 times over the past year! While traders might not buy and sell with each crossing, cases of high momentum are normally short-lived. The amount of trading in most technical analysis schemes racks up commission fees and short-term capital gains taxes, eating away at profits. More importantly, it takes away from the idea of holding a portfolio of great companies that can accrue wealth over a long time.

That's why, at, we recommend that individual investors establish a portfolio of well-managed companies with strong advantages over their competitors. In the end, we find that to be the best contributor to long-term wealth. More importantly, it'll spare you from sitting bleary-eyed in front of a computer with a Big Gulp full of coffee, frantically buying in and out of companies. But hey, if your idea of protecting your future is charting the ups and downs of moving average convergence-divergence charts, then Keryx Biopharmaceuticals looks like a sell right now. Just don't expect to hold it for very long.

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