What is the biggest marijuana company?

The answer to this question depends on how the term "marijuana company" is defined. Curaleaf Holdings (OTC:CURLF), a multistate cannabis operator, currently has the biggest market cap among companies in the cannabis industry. However, other companies with peripheral ties to the industry, such as Quest Diagnostics, are even larger.

How much is the marijuana industry worth?

Global marijuana industry revenue in 2026 is expected to reach $79.5 billion, according to Statista. This number includes medical and recreational cannabis plus cannabidiol (CBD) products.

Is the marijuana industry profitable?

Profitability in the marijuana industry varies from company to company. Some marijuana companies are consistently profitable, but many are not.

Will marijuana stocks ever recover?

Marijuana stocks could eventually rebound from the slump experienced in recent years, especially if major progress is made in relaxing U.S. federal regulations that negatively impact the cannabis industry. However, it's possible that many marijuana stocks won't reach their previous peak levels.

How can investors manage risk in marijuana stocks?

Investors can manage risk in marijuana stocks by:Diversifying their holdings (including potentially buying marijuana ETFs that own a basket of stocks).Considering investing in ancillary stocks that generate steady cash flow.Focusing on the same fundamental factors that apply to any stock.Limiting their initial investment.

How do changes in legislation impact marijuana stocks?

Legislative changes can significantly impact marijuana stocks. On the positive side, relaxation of restrictions on the use of marijuana or on the cannabis industry can provide upside catalysts to marijuana stocks. However, changes in legislation could also tighten restrictions on the cannabis industry, which would likely cause marijuana stocks to fall.

Best Marijuana Stocks for 2026 and How to Invest

By Keith Speights – Updated Apr 13, 2026 at 11:42 AM EST | Fact-checked by Margo Winton Parodi

Key Points

DEA reclassification of marijuana to Schedule III could boost cannabis industry growth.
Federal illegality and regulatory issues pose investment risks in the cannabis sector.
Understanding market dynamics is crucial before investing in marijuana stocks.

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Ticker Information Table
Name and ticker	Market cap	Dividend yield	Industry
Green Thumb Industries (OTC:GTBIF)	$1.6 billion	0.00%	Pharmaceuticals
Trulieve Cannabis (OTC:TCNNF)	$1.2 billion	0.00%	Pharmaceuticals
Innovative Industrial Properties (NYSE:IIPR)	$1.4 billion	15.00%	Industrial REITs
Quest Diagnostics (NYSE:DGX)	$21.2 billion	1.69%	Healthcare Providers and Services
Turning Point Brands (NYSE:TPB)	$1.6 billion	0.37%	Tobacco

Data as of Apr 14, 2026. Showing 5 of 5 tickers.

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OTC: GTBIF

Green Thumb Industries

Today's Change

(0.89%) $0.06

Current Price

$6.80

Key Data Points

Market Cap

$1.6B

Day's Range

$6.75 - $6.92

52wk Range

$4.80 - $10.43

Volume

40K

Avg Vol

583K

Gross Margin

45.90%

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OTC: TCNNF

Trulieve Cannabis

Today's Change

(3.02%) $0.19

Current Price

$6.49

Key Data Points

Market Cap

$1.2B

Day's Range

$6.26 - $6.50

52wk Range

$3.25 - $11.83

Volume

52K

Avg Vol

220K

Gross Margin

50.25%

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Trulieve Cannabis (TCNNF +2.86%) is the largest cannabis retailer in the U.S. It operates more than 230 retail cannabis stores in nine states, with 15 processing facilities in six states. The company dominates the market in its home state of Florida. It also claims market-leading positions in Arizona and Pennsylvania.

Support for legalizing recreational marijuana failed to achieve the required 60% threshold in Florida's 2024 elections. However, with almost 56% of the state's voters favoring legalization, Trulieve could still have a significant growth opportunity if the state legalizes recreational marijuana in the future.

Like Green Thumb, Trulieve's shares can currently only be traded on OTC markets in the U.S. The stock will likely be a big winner if federal marijuana reforms allow U.S. stock exchanges to list the shares of cannabis companies that operate in the U.S.

3. Innovative Industrial Properties

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NYSE: IIPR

Innovative Industrial Properties

Today's Change

(1.09%) $0.56

Current Price

$51.23

Key Data Points

Market Cap

$1.4B

Day's Range

$50.84 - $51.40

52wk Range

$44.58 - $59.83

Volume

1.1K

Avg Vol

302K

Gross Margin

60.80%

Dividend Yield

15.00%

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NYSE: DGX

Quest Diagnostics

Today's Change

(0.23%) $0.45

Current Price

$193.36

Key Data Points

Market Cap

$21B

Day's Range

$191.63 - $194.17

52wk Range

$160.02 - $213.50

Volume

4.2K

Avg Vol

982K

Gross Margin

31.93%

Dividend Yield

1.69%

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Quest Diagnostics (DGX +0.23%) might be a surprising pick for a list of marijuana stocks, as it's one of the world's largest providers of laboratory testing services.

How does Quest tie in with the cannabis industry? The widespread legalization of marijuana in states across the U.S. is driving increasing demand for drug testing in the workplace. Quest offers drug testing services and is certified by the U.S. Department of Health and Human Services for federally mandated drug testing of workers in some safety-sensitive fields.

Quest could be an attractive stock for more risk-averse investors looking to profit from the legalization of cannabis. The company has a long track record of success and is consistently profitable.

5. Turning Point Brands

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NYSE: TPB

Turning Point Brands

Today's Change

(-1.02%) $-0.85

Current Price

$82.39

Key Data Points

Market Cap

$1.6B

Day's Range

$82.39 - $83.79

52wk Range

$56.03 - $146.90

Volume

1.7K

Avg Vol

420K

Gross Margin

57.08%

Dividend Yield

0.37%

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Investing in Marijuana Stocks FAQ

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About the Author

Keith Speights is a contributing Motley Fool healthcare analyst covering publicly traded companies across pharmaceuticals, biotechnology, medical devices, technology, and marijuana. Prior to The Motley Fool, Keith was CEO of Constant Care Technology, a healthcare technology company; vice president of American HealthTech, a healthcare software company; and a director of operations for Blue Cross Blue Shield of Mississippi, a health insurer. He holds a B.S. in Industrial Engineering from Mississippi State University.

TMFFishBiz

Keith Speights has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Quest Diagnostics. The Motley Fool recommends Green Thumb Industries, Innovative Industrial Properties, and Turning Point Brands. The Motley Fool has a disclosure policy.

Best Marijuana Stocks for 2026 and How to Invest

Key Points

Key Data Points

Key Data Points

3. Innovative Industrial Properties

Key Data Points

Key Data Points

5. Turning Point Brands

Key Data Points

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Investing in Marijuana Stocks FAQ

What is the biggest marijuana company?

What is the biggest marijuana company?

How much is the marijuana industry worth?

How much is the marijuana industry worth?

Is the marijuana industry profitable?

Is the marijuana industry profitable?

Will marijuana stocks ever recover?

Will marijuana stocks ever recover?

How can investors manage risk in marijuana stocks?

How can investors manage risk in marijuana stocks?

How do changes in legislation impact marijuana stocks?

How do changes in legislation impact marijuana stocks?

About the Author

Read Next

Stocks Mentioned

Premium Investing Services

Investing in Marijuana Stocks FAQ

What is the biggest marijuana company?

What is the biggest marijuana company?

How much is the marijuana industry worth?

How much is the marijuana industry worth?

Is the marijuana industry profitable?

Is the marijuana industry profitable?

Will marijuana stocks ever recover?

Will marijuana stocks ever recover?

How can investors manage risk in marijuana stocks?

How can investors manage risk in marijuana stocks?

How do changes in legislation impact marijuana stocks?

How do changes in legislation impact marijuana stocks?

Best Pharmaceutical Stocks to Buy in 2026 and How to Invest in Them

Best Growth Stocks to Buy in 2026

Best Healthcare Stocks to Buy in 2026 and How to Invest in Them

Best Psychedelic Stocks to Buy in 2026 and How to Invest

Key Data Points

1. Green Thumb Industries

Benefits and risks of investing in marijuana stocks

Should you invest in marijuana stocks?

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FAQ

Five top marijuana stocks for 2026

Key Data Points

Key Data Points

Key Data Points

Key Data Points

2. Trulieve Cannabis

3. Innovative Industrial Properties

4. Quest Diagnostics

5. Turning Point Brands

How to buy marijuana stocks