Investing in Biotech Stocks in 2025

By Keith Speights – Updated Oct 3, 2025 at 2:44 AM | Fact-checked by Frank Bass

Key Points

Biotech stocks specialize in companies using living organisms to innovate in disease treatment.
Invest in biotechs with diverse drug pipelines and current market products to reduce investment risk.
Biotech investments can offer high returns even when other market sectors are underperforming.

Some scientists believe that we’re in the golden age of biotechnology. Scientific advances are creating new and previously unimaginable ways to treat and prevent diseases. Biotech stocks are a type of investment that focuses on companies specializing in biotechnology.

The biotech sector is also presenting exciting opportunities for investors. Many of the best biotech companies have both strong drug candidate pipelines and winning drugs already on the market.

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A biotech lab technician using multiple pipettes to load blood samples into test tubes. — Image source: Getty Images.

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Ticker Information Table
Name and ticker	Market cap	Dividend yield	Industry
Axsome Therapeutics (NASDAQ:AXSM)	$6.6 billion	0.00%	Pharmaceuticals
BioNTech Se (NASDAQ:BNTX)	$25.7 billion	0.00%	Biotechnology
Exelixis (NASDAQ:EXEL)	$9.7 billion	0.00%	Biotechnology
Regeneron Pharmaceuticals (NASDAQ:REGN)	$61.4 billion	0.30%	Biotechnology
Summit Therapeutics (NASDAQ:SMMT)	$13.9 billion	0.00%	Biotechnology
Vertex Pharmaceuticals (NASDAQ:VRTX)	$109.3 billion	0.00%	Biotechnology

Data as of Oct 22, 2025.

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1. Axsome Therapeutics

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NASDAQ: AXSM

Axsome Therapeutics

Today's Change

(-1.27%) $-1.67

Current Price

$129.72

Key Data Points

Market Cap

$7B

Day's Range

$127.49 - $131.75

52wk Range

$75.56 - $139.13

Volume

396K

Avg Vol

562K

Gross Margin

89.78%

Dividend Yield

N/A

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2. BioNTech

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NASDAQ: BNTX

BioNTech Se

Today's Change

(-0.62%) $-0.66

Current Price

$106.23

Key Data Points

Market Cap

$26B

Day's Range

$105.00 - $107.05

52wk Range

$81.20 - $129.27

Volume

797K

Avg Vol

878K

Gross Margin

79.80%

Dividend Yield

N/A

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NASDAQ: EXEL

Exelixis

Today's Change

(-0.14%) $-0.05

Current Price

$36.08

Key Data Points

Market Cap

$10B

Day's Range

$35.44 - $36.45

52wk Range

$27.86 - $49.62

Volume

3.1M

Avg Vol

Gross Margin

96.59%

Dividend Yield

N/A

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NASDAQ: REGN

Regeneron Pharmaceuticals

Today's Change

(0.95%) $5.53

Current Price

$584.87

Key Data Points

Market Cap

$61B

Day's Range

$578.72 - $588.50

52wk Range

$476.49 - $959.60

Volume

35K

Avg Vol

Gross Margin

81.98%

Dividend Yield

0.00%

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5. Summit Therapeutics

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NASDAQ: SMMT

Summit Therapeutics

Today's Change

(2.35%) $0.44

Current Price

$19.18

Key Data Points

Market Cap

$14B

Day's Range

$18.56 - $20.50

52wk Range

$15.55 - $36.91

Volume

154K

Avg Vol

3.9M

Gross Margin

0.00%

Dividend Yield

N/A

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6. Vertex Pharmaceuticals

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NASDAQ: VRTX

Vertex Pharmaceuticals

Today's Change

(0.04%) $0.17

Current Price

$426.44

Key Data Points

Market Cap

$109B

Day's Range

$421.94 - $431.81

52wk Range

$362.50 - $519.88

Volume

1.7M

Avg Vol

1.8M

Gross Margin

86.08%

Dividend Yield

N/A

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Woman scientist in lab holding up test tube. — Image source: Getty Images.

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Related investing topics

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Biotech vs. Pharma: What's the Difference?

While there is a lot of overlap between biotech and pharma, there are some key differences.

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About the Author

Keith Speights is a contributing Motley Fool healthcare analyst covering publicly traded companies across pharmaceuticals, biotechnology, medical devices, technology, and marijuana. Prior to The Motley Fool, Keith was CEO of Constant Care Technology, a healthcare technology company; vice president of American HealthTech, a healthcare software company; and a director of operations for Blue Cross Blue Shield of Mississippi, a health insurer. He holds a B.S. in Industrial Engineering from Mississippi State University.

TMFFishBiz

Keith Speights has positions in Bristol Myers Squibb, Pfizer, and Vertex Pharmaceuticals. The Motley Fool has positions in and recommends Axsome Therapeutics, Bristol Myers Squibb, Exelixis, Merck, Pfizer, Regeneron Pharmaceuticals, Summit Therapeutics, and Vertex Pharmaceuticals. The Motley Fool recommends BioNTech Se. The Motley Fool has a disclosure policy.