Investing in Marijuana ETFs

Here's what you need to know about the top marijuana ETFs.

By Keith Speights – Updated Jun 15, 2025 at 12:26 AM | Fact-checked by Frank Bass

Key Points

The global cannabis market may reach $444 billion by 2030, growing at a 34% annual rate.
Marijuana ETFs offer diversification, lowering risk versus individual stocks.
AdvisorShares Pure U.S. Cannabis ETF is the largest marijuana ETF and heavily invests in major U.S. cannabis companies.

Cannabis is projected to be a $444 billion global market by 2030, according to Forbes Business Insights. The industry is expected to grow by an impressive compound annual growth rate of 34%.

Investors have several ways to potentially profit from this tremendous growth. You can invest in specific marijuana stocks, but another alternative is to invest in exchange-traded funds (ETFs) that focus on the cannabis industry.

A cannabis leaf on top of a $100 bill. — Image source: Getty Images.

The main benefit of buying marijuana ETFs is that your money is spread across a basket of stocks, which can lower your risk compared to investing in only a few individual stocks. Here's what you need to know about the top marijuana ETFs on the market.

Top marijuana ETFs in 2025

Below are six top marijuana ETFs ranked by assets under management.

Data source: Yahoo! Finance and ETF websites. Data current as of June 6, 2025. ETF = exchange-traded fund.
ETF	Assets Under Management	Net Expense Ratio
AdvisorShares Pure U.S. Cannabis ETF (NYSEMKT:MSOS)	$308.9 million	0.77%
Amplify Alternative Harvest ETF (NYSEMKT:MJ)	$103.8 million	0.76%
Global X Marijuana Life Sciences Index ETF (OTC:HMLSF)	$44.9 million	0.98%
AdvisorShares Pure Cannabis ETF (NYSEMKT:YOLO)	$24.9 million	1.12%
Amplify Seymour Cannabis ETF (NYSEMKT:CNBS)	$55.9 million	0.76%
Cambria Cannabis ETF (NYSEMKT:TOKE)	$11.7 million	0.43%

1. AdvisorShares Pure U.S. Cannabis ETF

The largest marijuana ETF, based on assets under management, is the AdvisorShares Pure U.S. Cannabis ETF (MSOS +5.63%). It's the first ETF to focus exclusively on the U.S. cannabis market.

This ETF currently has more than 20 holdings, including U.S. marijuana stocks and swaps (derivative contracts, where the values or cash flows of one asset are exchanged for another). Its top positions include swaps for Green Thumb Industries (GTBIF +6.39%), Trulieve Cannabis (TCNNF +2.99%), Curaleaf Holdings (CURLF +9.33%), Glass House Brands (OTC:GLASF), Cresco Labs (CRLBF +9.01%), and Verano Holdings (OTC:VRNO.F).

It's possible that the ETF's focus on the U.S. market could give investors greater growth opportunities than other ETFs. Although marijuana remains illegal at the federal level in the U.S., many states have legalized marijuana for medical and/or recreational use.

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About the Author

Keith Speights is a contributing Motley Fool healthcare analyst covering publicly traded companies across pharmaceuticals, biotechnology, medical devices, technology, and marijuana. Prior to The Motley Fool, Keith was CEO of Constant Care Technology, a healthcare technology company; vice president of American HealthTech, a healthcare software company; and a director of operations for Blue Cross Blue Shield of Mississippi, a health insurer. He holds a B.S. in Industrial Engineering from Mississippi State University.

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Keith Speights has no position in any of the stocks mentioned. The Motley Fool has positions in and recommends Cronos Group. The Motley Fool recommends British American Tobacco P.l.c., Cresco Labs, Green Thumb Industries, Innovative Industrial Properties, Philip Morris International, SNDL, Scotts Miracle-Gro, and Tilray Brands and recommends the following options: long January 2026 $40 calls on British American Tobacco and short January 2026 $40 puts on British American Tobacco. The Motley Fool has a disclosure policy.